Kevin Ahern is a professor at the Oregon State University who have created several musics about biochemistry for his students. Here is the lyrics of the music about gluconeogenesis (based on the song Supercalifragilisticexpialidocious) and the link for the download of the .mp3 file.
http://www.mediafire.com/?8rwy9fzwg2ou9rm
When cells have lots of ATP and NADH too
They strive to store this energy as sugar yes they do
Inside of mitochondria they start with pyruvate
(slow) Carboxylating it to make oxaloacetate
(slow) Carboxylating it to make oxaloacetate
Oh gluconeogenesis is so exhilarating
Memorizing it can really be exasperating
Liver cells require it so there’s no need for debating
Gluconeogenesis is so exhilarating
Oxaloacetate has got to turn to PEP
Employing energy that comes from breaking GTP
From there it goes to make a couple phosphoglycerates
(slow) Exploiting ee-nolase and mutase’ catalytic traits
Oh gluconeogenesis is liver’s specialty
Producing sugar for the body most admirably
Six ATPs per glucose is the needed energy*
Gluconeogenesis is liver’s specialty
Oh glucose, glucose joy to me
Glucose, glucose joy to me
Converting phosphoglycerate to 1,3BPG
Requires a phosphate that includes A-T-P energy
Reduction with electrons gives us all an N-A-D
(slow) G3P’s isomerized to make D-H-A-P Oh gluconeogenesis is anabolic bliss
Reversing seven mechanisms of glycolysis
To do well on the final students have to learn all this
Gluconeogenesis is anabolic bliss
Oh, glucose, glucose factory
Glucose, glucose factory
The aldolase reaction puts together pieces so
A fructose molecule is made with two phosphates in tow
And one of these gets cleaved off by a fructose phosphatase
(slow) F2,6BP's acting blocking path-a-waysAnd
Oh gluconeogenesis a pathway to revere
That makes a ton of glucose when it kicks into high gear
The cell's a masterminding metabolic engineer
Gluconeogenesis a pathway to revere
Oh glucose, glucose jubilee
Glucose, glucose jubilee
From F6P to G6P, that is the final phase
The enzyme catalyzing it is an isomerase
Then G6P drops phosphate and a glucose it becomes
(slow) Inside the tiny endoplasmic-al reticulumsUnless
Oh gluconeogenesis is not so very hard
I know that on the final we will not be caught off guard
'Cause our professor lets us use a filled out index card
Gluconeogenesis is not so very hard
*Actually, you need two NADHs too, but that wouldn't fit the rhyme
Oh, glucose, glucose come to be
Glucose, glucose come to be
