Krebs Cycle (main aspects)

Krebs cycle

- Type of metabolic pathway: catabolic, cyclic

- Main goal: energy production from acetyl-CoA oxidation

- Subcellular localization: mitochondrial matrix

- Conditions required to occur: aerobic

- Number of biochemical reactions: 8

- Energetic output (per acetyl-CoA molecule): +3 NADH, 1 FADH2 e +1 GTP

- Final product (per acetyl-CoA molecule): 2 CO₂

Glycolysis (main aspects)

I have decided to begin with an overview about metabolic pathways. Before I start to detail those pathways, I will reserve the first posts to an abstract of the most important aspects of the different processes of the so-called main metabolism.

Glicolysis

- Type of metabolic pathway: catabolic, linear

- Main goal: energy production from glucose degradation

- Subcellular localization: cytosol

- Conditions required to occur: aerobic and/or anaerobic

- Number of biochemical reactions: 10

- Energetic output (per glucose molecule): +2 ATP e +2 NADH

- Final product (per glucose molecule): 2 piruvate

Fates of pyruvate (main aspects)

Lactic fermentation

- Main goal: to regenerate NAD⁺ through the reduction of pyruvate

- Subcellular localization: cytosol

- Conditions required to occur: anaerobic and/or absence of mitochondria

- Number of biochemical reactions: 1

- Energetic output (per pyruvate molecule): -1 NADH

- Final product (per pyruvate molecule): 1 lactate

Pyruvate oxidation

- Type of metabolic pathway: catabolic, linear

- Main goal: energy production from pyruvate oxidation

- Subcellular localization: mitochondrial matrix

- Conditions required to occur: aerobic

- Number of biochemical reactions: 1

- Energetic output (per pyruvate molecule): +1NADH

- Final product (per pyruvate molecule): 1 acetyl-CoA