Music about the thermodynamics of metabolism
The song Yesterday, from The Beatles, was used to create a music about the thermodynamics of the cellular metabolism. Here it is the final result...
http://www.mediafire.com/?2fqq9en6ujrktbn
The Cell's Lament
Instructor sings
Woe is me
My substrates are losing entropy
Causing gains in Gibbs free energy
Oh I can't lose no en - tro- py
Re-a-lly
I could use a source of enthalpy
To combat the rise in Delta G
Oh I believe in enthalpy
Everyone sings
I crave en-er-gy
Don't you see?
It's getting worse
My re-actions all
Soon will stall
And then rever-r-r-se
Instructor sings
ATP
It's the metabolic currency
Guess I'll spend a bit judiciously
To help reduce the Delta G
Help reduce the Delta G
http://www.mediafire.com/?2fqq9en6ujrktbn
The Cell's Lament
Instructor sings
Woe is me
My substrates are losing entropy
Causing gains in Gibbs free energy
Oh I can't lose no en - tro- py
Re-a-lly
I could use a source of enthalpy
To combat the rise in Delta G
Oh I believe in enthalpy
Everyone sings
I crave en-er-gy
Don't you see?
It's getting worse
My re-actions all
Soon will stall
And then rever-r-r-se
Instructor sings
ATP
It's the metabolic currency
Guess I'll spend a bit judiciously
To help reduce the Delta G
Help reduce the Delta G
Peacock and family portrait
Well I've been woking at Mick's on the peacock. And spending some time at home on the family portrait. I think I learned a couple things from my commission works I felt I needed to put into practice. So I think were where we need to be on the family thing but the peacock is still giving me troubles. But I'm sure I get her into shape its just a question of time.
Merry Christmas!
I wish to all visitors of World of Biochemistry, and particularly to its followers, a very Merry Christmas, fukk of peace and joy! :)
Portrait two
Well today was the final touches to the other portrait commission. Now its all down to smashing out the peacock. Its always a chalange to re-do a piece but I'm confident that she will work out to everyone satisfaction.
Micks Irish pub
Thiol group
The thiol group, or sulphydryl group or mercaptan group, is the functional group –SH. The prefix "thio" in this, and other functional groups, means that it has a sulfur atom instead of an oxygen (for example, there are also the thioester and thioether groups...). In this case, the ending suffix "ol", tells us that indeed this group is a group derived from an alcohol. That is, instead of the hydroxyl group –OH, we have sulfur in the place of the oxygen. One very important difference with respect to hydroxyl groups is related to the fact that the thiol groups present a weak acid behavior.
Since it has sulfur in its composition, the presence of thiol groups often confers to molecules an unpleasant odor.
Since it has sulfur in its composition, the presence of thiol groups often confers to molecules an unpleasant odor.
Blondie
My phone rang. I received one of the most important request of my career. I was asked to the makeup for a legendary musical icon...Debbie Harry. I almost pass out.
Not only am I a fan of Debbie Harry and Blondie they have also been one of the biggest inspirations for my art and personal fashion. Throughout my career I have worked with many celebrities but this one was an awe inspiring moment. Debbie did not disappoint...she is smart, funny, sweet, easy going and fun. We talked about movies and fashion while I did her makeup for two separate shoots.
Featured above is the video is the German/French channel ARTE documentary "Queens of Pop". Take a glimpse of my makeup for Debbie Harry.
If anyone speaks German or French...I would love a translation!
Game about acids and bases (3)
Here it goes the link to a game about acids and bases.
http://pbskids.org/zoom/games/kitchenchemistry/virtual-start.html
http://pbskids.org/zoom/games/kitchenchemistry/virtual-start.html
Famous sentence (6)
Age is an issue of mind over matter. If you don’t mind, it doesn’t matter." - Mark Twain
Music about biochemistry (2)
Here it goes another song about biochemistry, this time with the interesting name Brain farts. :) It was adapted from the Raindrops Keep Fallin' On My Head.
http://www.mediafire.com/?2zsrhqcgs2gkg2u
Brain Farts Just Happen In My Head
Brain farts just happen in my head
I think it might be due to something Kevin said
Bi-o-che-mis-try
Gets brain farts a poppin' in my head and they're poppin'
So I just wiped out the teardrops from my eyes
And told my brain it had to do some men-tal exer-cise
Burn some ATP
So brain farts can stop inside my head they'll be stoppin'
'Cause there's one thing I've learned
When energy increases it sure pleases
My mental state - I'm doing great as tension eases
Now brain farts don't happen in my head
So I'm sure the final will be easier instead
Cyclic AMP
Stops brain farts from poppin' in my head they're not poppin'
Thanks to caffeine
Nothin's worryin' me
Animation about a proton pump
Here it is the link to download an animation about the active transport of H+.
http://www.mediafire.com/?p4jouhjecojumdn
http://www.mediafire.com/?p4jouhjecojumdn
Ether group
The ether functional group is characterized by the presence of an oxygen atom shared by two carbons (can be alkyl or aryl groups). It is therefore a functional group that appears in an internal position within the molecules. Its general formula is C1-O-C2.
The C-O-C bond angle has about 104.5 °, with a bonding distance of 140pm. The ether group is a polar functional group, because the COC bond angle is not 180°, which impairs the molecule dipoles to cancel each other. Although it cannot function as an H donor in hydrogen bonds, it can function as an acceptor of them.
In biochemistry, the ether groups are present, for example, in the O-glycosidic bonds.
Scientific jokes (9)
Did you hear about the biologist who had twins?
She baptized one and kept the other as a control.
She baptized one and kept the other as a control.
Game about acids and bases (2)
Here it is a link to a game about acids and bases, in a more physiological perspective.
http://www.funtrivia.com/playquiz/quiz2398821b771b8.html
http://www.funtrivia.com/playquiz/quiz2398821b771b8.html
Music about biochemistry
Here it goes one more Christmas song (Oh Christmas tree) that was used to make a different song, this time about Biochemistry.
Biochemistry/Biochemistry
Biochemistry Biochemistry
I wish that I were wiser
I feel I'm in way o'er my head
I need a new advisor
My courses really shouldn't be
Such metabolic misery
Biochemistry Biochemistry
I wish that I were wiser
Biochemistry Biochemistry
Reactions make me shiver
They're in my heart and in my lungs
They're even in my liver
I promise I would not complain
If I could store them in my brain
Biochemistry Biochemistry
I wish that I were wiser
Biochemistry Biochemistry
I'm truly in a panic
Your mechanisms murder me
I should have learned organic
For all I have to memorize
I ought to win the Nobel Prize.
Biochemistry Biochemistry
I wish that I were wiser
Biochemistry/Biochemistry
Biochemistry Biochemistry
I wish that I were wiser
I feel I'm in way o'er my head
I need a new advisor
My courses really shouldn't be
Such metabolic misery
Biochemistry Biochemistry
I wish that I were wiser
Biochemistry Biochemistry
Reactions make me shiver
They're in my heart and in my lungs
They're even in my liver
I promise I would not complain
If I could store them in my brain
Biochemistry Biochemistry
I wish that I were wiser
Biochemistry Biochemistry
I'm truly in a panic
Your mechanisms murder me
I should have learned organic
For all I have to memorize
I ought to win the Nobel Prize.
Biochemistry Biochemistry
I wish that I were wiser
Animation about crossingover
Here it is a link to download an animation about crossingover.
http://www.mediafire.com/?3fbcjo1l1c4kjw6
http://www.mediafire.com/?3fbcjo1l1c4kjw6
Amide group
The amide group is originated when a carboxyl group reacts with an amine group. It is characterized by the presence of a carbon bounded to an oxygen through a double bond and to a nitrogen via a single bond.
Indeed, though this is the most common representation, the amide group displays an electronic delocalization involving the oxygen, carbon and nitrogen atoms. That is, the bound between carbon and oxygen is partially double, and the same is valid for the bound between the carbon and the nitrogen. This causes the amide group to present a rigid conformation, where these three atoms define a plane.
Indeed, though this is the most common representation, the amide group displays an electronic delocalization involving the oxygen, carbon and nitrogen atoms. That is, the bound between carbon and oxygen is partially double, and the same is valid for the bound between the carbon and the nitrogen. This causes the amide group to present a rigid conformation, where these three atoms define a plane.
The amide group can be located at the end of a molecule, in which case the nitrogen is connected to two hydrogens, or may be in an internal position, causing the nitrogen to be connected to a hydrogen and a second carbon, or two different carbons.
Despite having a nitrogen atom, the amide group does not have a significant alkaline behavior.
In biochemistry the amide group appears in a prominent position because it is the functional group that exists in the peptide bonds.
In biochemistry the amide group appears in a prominent position because it is the functional group that exists in the peptide bonds.
The amide groups can be identified by infrared spectroscopy (it shows a VCO band at about 1650 cm-1).
Final Touches
Well dead line is almost upon us. So Its do or die. I'm reasonably happy with my works, fortunately I think I can let them go. Hopefully there well received.
Game to kill aminoacids
This is my favourite biochemical game. You can download it with the link:
http://www.mediafire.com/?vf10cvmo6nsray9
http://www.mediafire.com/?vf10cvmo6nsray9
Music about DNA
Is there anyone who does not know the music YMCA? Here it is a version of it about DNA... :)
http://www.mediafire.com/?v0lk6tqayxgjpcb
http://www.mediafire.com/?v0lk6tqayxgjpcb
B-DNA
Phosphates
Are in nucleotides
I say phosphates
Cover bases inside
I say phosphates
Span the 5 and 3 primes
There's no need - to - be - all - mixed - up
Bases
Carry info you see
I say bases
Are all complement'ry
I say bases
Like A,T,G and C
They have got - to - be – all - paired - up
It's fun to play with some
B-DNA
It's got a boatload of
G-C-T-A
It's got everything
A polymerase needs
When you melt all the A's and T's
It's fun to play with some
B-DNA
It's got a boatload of
G-C-T-A
You can make RNAs
With a po-ly-mer-ase
Just by pairing up U's with A's
Proteins
Full of amino A's
I say proteins
Come from mRNAs
I say proteins
Require tRNAs
There is more – you - need - to – trans-late
Codons
Like our friend U-A-C
I say codons
Come in clusters of three
I say codons
Have one base wobble –ee
Now you can - go - forth - and - tran-slate
It's fun to play with some
B-DNA
It's got a boatload of
G-C-T-A
All those hydrogen Bs
And right-hand he-li-ces
Anti-par-a-llel fives and threes
It's fun to play with some
B-DNA
It's got a boatload of
G-C-T-A
All those hydrogen Bs
And right-hand he-li-ces
Anti-par-a-llel fives and threes
It's fun to play with some
B-DNA
It's got a boatload of
G-C-T-A
All those hydrogen Bs
And right-hand he-li-ces
Anti-par-a-llel fives and threes
Time keeps on ticking
Ester group
The ester group is characterized by being an internal functional group, that is, it does not appear in the ends of the molecules. It presents two oxygen atoms bound to the same carbon atom, one through a double bound and the other one through a single one (R1-COO-R2). It is a neutral polar group, that is, it does not possess acid or basic properties. It can establish hydrogen bounds, acting as a H acceptor.
It is formed by the reaction of a carboxyl and a hydroxyl functional groups. Putting it in a simple way, it is the result of the substitution of the hydrogen atom of a carboxyl group by an organic portion.
It can be identified by infrared sepctroscopy (it presents a band between 1730-1750 cm-1).
Animation about southern blot
Here it goes the link to download an animation about southern blot.
http://www.mediafire.com/?nrloo2h3q240cy7
http://www.mediafire.com/?nrloo2h3q240cy7
Music about fermentation (2)
This is one more Christmas song (Rudolph the Red-Nosed Reindeer) that turned out into a song about biochemistry, this time about fermentation.
http://www.mediafire.com/?5afx4u8ed6uk80l
Substrate phosphorylation’s
How they make their ATP
With no electron takers
They need an alternative
Isn’t fermentation great?
For reducing pyruvate!
Ask yourself when you’re drinking
“Where do we get alcohol?”
http://www.mediafire.com/?5afx4u8ed6uk80l
The Alcohol Song
Cells go through fermentation
When they’re out of NADSubstrate phosphorylation’s
How they make their ATP
Cells are efficient makers ( . . .of)
Energy on which to liveWith no electron takers
They need an alternative
Oh glycolysis would stop
Without NADIsn’t fermentation great?
For reducing pyruvate!
And if you might be thinking
“Man this isn’t cool at all”Ask yourself when you’re drinking
“Where do we get alcohol?”
Amino group
The amine group is characterized by the presence of a nitrogen atom with a pair of non-bonding electrons. It is derived from ammonia, where one or more hydrogens have been replaced by other atoms.
The amines can be divided into primary, secondary and tertiary. The primaries are those in which only one of three hydrogen atoms of ammonia was replaced by an alkyl chain. The secondary amines have two alkyl chains and the tertiary have three. The secondary and tertiary amines may be presented in a linear or cyclic form.The amines may be designated in different ways. Typically, it is used the prefix amino-("aminoacid", for example) or the suffix-amine ("glucosamine," for example). When there is a substitution in the amino group, it is named starting with the prefix N-.
The amines can establish hydrogen bonds, since they have one H atom attached to a very electronegative atom (N in this case).
The amines act as weak bases, as they can capture a H+, due to the existence of a pair of non-bonding electrons in the nitrogen atom. They are the most relevant alkaline functional group in biochemistry.
The amines can establish hydrogen bonds, since they have one H atom attached to a very electronegative atom (N in this case).
The amines act as weak bases, as they can capture a H+, due to the existence of a pair of non-bonding electrons in the nitrogen atom. They are the most relevant alkaline functional group in biochemistry.
Blue Ganesha
Very often custom tattoos are needed in film and television to complete the look for an actors character. I received a request to design a few tattoo designs for a very special episode of Nurse Jackie in the new season airing March 2012. Utilizing a new technique that I recently learned, I completed the process of the sketch to my first all blue mono-toned painting. The designs are then turned into a professional tattoo transfer to recreate the look of an authentic tattoo. Stay tuned for more details about the tattoos on Nurse Jackie!
Music about hemoglobin
Christmas is becoming near and a well known Christmas song (Santa Claus is Coming to Town) was adapted to describe the way hemoglobin works.
Oh isn't it great
What proteins can do
Especially ones that bind to O
Hemoglobin's moving around
Inside of the lungs
It picks up the baitAnd changes itself from T to R state
Hemoglobin's moving around
The proto-porphyrin system
Its iron makes such a sceneArising when an O binds
Pulling up on histidine
The binding occurs
Cooperatively
Thanks to changes qua-ter-nar-y
Hemoglobin's moving around
It exits the lungs
Engorged with O
In search of a working body tissue
Hemoglobin's moving aroundThe proton concentration
Is high and has a role
Between the alpha betas
It finds imidazole
To empty their loads
The globins decree"We need to bind 2,3BPG"
Hemoglobin's moving around
The stage is thus set
For grabbing a few
Cellular dumps of CO
Hemoglobin's moving around
And then inside the lungs it
Discovers ox-y-gen
And dumps the CO off
To start all o'er agin
So see how this works
You better expect
To have to describe the Bohr effect
Hemoglobin's moving around
Famous sentence (3)
"The essence of life is statistical improbability on a colossal scale.” - Richard Dawkins.
Beatles sketch
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